The H.E.A.R.T. Center will focus on three pivotal research themes. The first, ‘Interdisciplinary Approaches to Human-Agent Interaction,’ aims to unify disparate fields to develop a cohesive understanding of how humans and agents interact in various contexts. The second theme, ‘Ethical and Social Implications of Human-Agent Collaboration,’ will delve into the moral and societal facets of these partnerships, ensuring that advancements are aligned with ethical standards and contribute positively to society. Lastly, ‘Enhancing Human Flourishing through Agent Collaboration’ will explore how these technologies can be leveraged to improve quality of life, productivity, and personal fulfillment. Together, these themes will guide the center’s research towards meaningful and impactful applications.